Kinase Kinetic Selectivity Profiling
Translation kinetic selectivity profiles into early safety guidance
Over the course of dosing, a drug showing minimal toxicity and long residence time for its main target but short residence time for secondary targets is better tolerated.
Enzymlogic determines the residence time of your compounds when bound to the kinase panel of your choice to evaluate their pharmacological behavior.
Features & benefits:
• Determination of affinity and residence time in one assay format
• Prediction of pharmacological selectivity profiles
• Identification of potential new uses
• Quantify binding to inactive or low activity kinases
• Rapid turnaround time
• Accurate and reproducible data
Related links:
Developed by Web4Bio