Product


ZeGenesis
ZeClinics provides its expertise in transgenic manipulation and zebrafish biology for generating mutant and/or knock-in lines, models of human diseases, and later phenotype them, in order to use them for custom drug screenings.
 
Large genetic disease variability and limitations of murine models for human diseases open the need for innovative models where mutants can be easily validated and generated. Zebrafish allows that specific and high efficient transgenesis and mutational studies, with capability for generating a great number of economic and highly informative cell line specific transgenic lines or/and genetic disease models.

ZeClinics proposes to generate several transgenic/knock-in/conditional knock-out (Flox zebrafish) stable zebrafish colonies through Tol2 transgenesis technology (4 months/F1) and CRISPR/Cas9 genome editing technology (10 months/F2).
LICENCED BY THE BROAD INSTITUTE, MIT, HARVARD UNIVERSITY.
 
 
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