Pharmaron's DMPK Webinar

Join our DMPK webinar “DMPK for ADCs: Measure the Parts, Model the Whole, Decide Early” on 3 February 2026 at 8 am PT / 11 am ET / 4 pm GMT!

Antibody–drug conjugates (ADCs) hold enormous potential, but their complexity means the right DMPK approach is needed from the start. The presenters—Kati Räsänen, Quigyu Cui, and Tuomas Tervahauta—will walk through how antibody, linker, and payload features influence exposure, efficacy, and safety, and what that means for smarter study design.

Key takeaways:

• ADC fundamentals: Explore antibody, linker, and payload roles and how they influence PK and stability
• Mastering detection strategies: Find out which assays (LBA vs LC–MS/hybrid) to use for intact ADC, total antibody, free payload, and metabolite formation/identification
• How to address critical DMPK challenges such as: DAR distribution, linker stability, payload exposure, and immunogenicity considerations
• Apply PK/PD principles for decision-making: Design studies that link exposure to effect and set transparent go/no-go criteria early.

Register now, here.