ATL-001b: Porphyria Cutanea Tarda (PCT)

PCT is the most common of porphyries and it encompasses a group of acquired and familial disorders in which activity of the uroporphyrinogen decarboxylase (UROD) is deficient. In Atlas, we are currently exploring the possibility of applying pharmacological chaperones to improve heme homeostasis in PCT patients. This project is at the lead validation of therapeutic chaperones.